“Look at Me” can often be done with a chin rub and slow eye blinks.

When behavior problems arise, your vet may recommend drug therapy and environmental changes for your cat. These interventions work best when coordinated with a behavior modification plan.

What is behavior modification? What does behavior modification for cats involve?

behavior modification for cats – more than just training and medication


Behavior modification is a type of behavior therapy. It has its roots in the work of B. F. Skinner in the 1930’s. Skinner was psychologist who believed behavior is a response to an organism’s environment and is not a consequence of mental states (beliefs, memories, desires, plans) (Reference 1).

Skinner came up with the theory of operant conditioning. In operant conditioning, reinforcement and punishment are used to encourage or discourage behaviors (Reference 2).

Reinforce the Behavior – Make It Happen Again!

Add Something “Good” Take Away Something “Bad”
If you reward your cat for sitting with his favorite treat, he is more likely to sit the next time you ask. If you stop trimming your cat’s nails every time she growls or hisses, you are reinforcing her behavior of hissing and growling at nail trims by “removing” the unpleasant nail trim.

Punish the Behavior – Make It Stop Happening

Add Something “Unpleasant” Take Away Something “Good”
If you spray your cat with water when she jumps on the counter, she may be less likely to jump up on the counter. Your cat claws at your hand for a treat. If you put the treat behind your back, the cat learns that the treat goes away when she swats at your hand.

Operant conditioning forms the basis of many training methods.  It appears to be pretty straight-forward: can we just reward the cat for using the litter box and spray her with water if she doesn’t? 

Problem behaviors involve more than just a stimulus and a conditioned response.  Operant conditioning  does not take into account the emotional state of an animal. It may be difficult to positively reinforce or punish an animal that is fearful.

To modify or change problem behaviors, the animal’s emotional state must be addressed. Teaching a cat or dog a substitute behavior for the undesired behavior or medicating him does not teach him how to respond to other stressful situations in his life.

Christine Calder, a member the American College of Veterinary Behaviorists, describes a five step process in working with problem behaviors in dogs (Reference 3).

  1.  Avoid all the things that cause the behavior.
  2. Open the lines of the communication – learn body language; stop punishment.
  3. Build a toolbox of known behaviors such as voluntary eye contact, touch, or a chin rest.
  4. Teach the animal to relax.
  5. Systematic desensitization and Counter Conditioning (to what triggers the behavior).

 Behavior modification for cats can follow this five-step plan.

You may have gotten a new dog or your young nephew comes to stay with you.  Your cat finds these new additions terrifying so she hides under the bed to be safe.  She does not use her litter box because she is afraid the dog or the child will be there. You try to adapt the environment to accommodate your cat and the newcomers but your cat remains fearful. 

Behavior Modification for Cats- More Than Just Training and Medication


  1. Avoid Triggers: We offer the kitty the sanctuary of a room or place in the house off-limits to the dog or child. This area has all the cat’s resources: litter box, cat tree, food and water.
  2. Establishing communication: Spend time with your cat, coaxing her to come to you; brush or pet her if she likes it. Learn her body language so that you know when she is done interacting (see “How to interact with your cat” ). Have your nephew also learn cat body language. Stop punishment: no spraying with water bottles; speak to your cat quietly with a pleasant tone.
  3. Toolbox of known behaviors: For a cat, these may be targeting on your finger or a stick, and learning to pay attention to you through eye contact.
  4. Teach the cat to relax: A cat who is relaxed is calm. She is able to devote more of her energy to learn how to cope with new situations. When the cat can relax on cue, she is able to choose a calm state. We can work up to asking for calm behavior when the dog or child is nearby.
  5. Desensitization: In this case, we introduce the cat to the dog or child in a safe situation. The dog or child is separated from the cat (use a barricade as needed) and the cat can come or go as she pleases. Gradually the distance between the cat and the dog or child is decreased.
  6. Counter-Conditioning: Previously, the cat associated the dog or child with being anxious or fearful. If she can be calm when dog  is on the other side of the barricade, we can start to form some new associations using high-value treats or other things the cat likes, such as being brushed.  With supervision, your nephew may be able offer your cat treats or brush her.

Behavior modification for cats is more than just substituting a desirable behavior in place of a problem behavior.  For the intervention to work, the emotional state of the cat has to be considered.  We need to give the cat a break from the stressful situation, then establish communication with cat.  We need the cat to trust us and look to us for guidance. Teaching the cat to relax and getting accustomed to what triggered the behavior are the final steps of the behavior modification plan.  The services of a cat behavior professional can be helpful in these situations.

references

  1. B.F. Skinner (1904-1990) Advocacy of Behaviorism and its Application to Psychology and Life
    Operant Conditioning and the Law of Effect.  https://psychology.fas.harvard.edu/people/b-f-skinner Viewed 5/2024.
  2. Cherry, Kendra. What is Operant Conditioning? February 24, 2023. https://www.verywellmind.com/operant-conditioning-a2-2794863  Viewed 5/2024.
  3. Calder, Christine D. Behavior Modification for Dogs. Behavior Bytes. December 28, 2022. https://cattledogpublishing.com/blog/behavior-modification-for-dogs/ Viewed 5/2024.

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Sometimes, fear and anxiety can make it difficult for a cat to cope with her daily life. Perhaps there has been a change in the environment – a new cat or dog comes to live in the home or a new born baby comes home one day.

A diligent owner tries to adapt the environment to accommodate the cat and the newcomers.   Sometimes, the resident kitty remains upset, hiding under the bed and not the using the litter box regularly. 

So, off to the vet for kitty. The vet may prescribe a behavior medication for a cat to reduce anxiety and allow the cat to start to acclimate to the changes in her world (Reference 1).

Can Behavior Medication for a Cat Help?


Daily behavior medications may be prescribed for cats due to:

  • anxiety
  • fearful behavior or aggression
  • inter-cat aggression
  • urine marking
  • overgrooming due to anxiety or other psychological reasons

How Does a Daily Behavior Medication for a Cat Work?


Most of the daily drugs prescribed for feline behavior problems involve the neurotransmitter serotonin.

Serotonin is a neurotransmitter, a chemical that transmits signals from a nerve to another nerve, muscle cell or gland. In humans, serotonin regulates behavior, mood, memory and metabolic processes in the intestines (Reference 3). Serotonin is thought to perform a similar function in cats, inducing feelings of happiness and calmness.

The most common drugs used to treat feline behavior problems include:

  • fluoxetine (human analog is Prozac)
  • clomipramine
  • buspirone

FLUOXETINE

Fluoxetine is a Sustained Serotonin Re-uptake Inhibitor (SSRI). It works by blocking the “reuptake” of serotonin, interfering with the metabolic “recycling” of serotonin and, consequently, serotonin actively transmits its messages for a longer period of time.

Time to full effect
Initially, there is an excess of serotonin due to the medication. Serotonin receptors are overwhelmed and you may see side effects such as decreased appetite and activity, and decreased grooming. But over 4-6 weeks, most of the receptors become less sensitive to the excess serotonin and the side effects abate (Reference 2).

Fluoxetine is the “go-to” daily behavior medication for a cat for most cases of feline anxiety, aggression, and house-soiling.

CLOMIPRAMINE

Clomipramine not only blocks the reuptake of serotonin, it also blocks reuptake of norepinephrine, a neurotransmitter responsible for the emotions underlying the “fight or flight” response. Most of the benefits of clomipramine are due to the action of serotonin, although norepinephrine also regulates anxiety and behavior.

Clomipramine has an antihistamine effect that contributes an additional calming effect similar to the sleepiness you may experience when taking allergy drugs such as benadryl.

Clomipramine reaches full effect in 4 weeks. There is more of a tendency toward side effects such as sedation, dry eye, dry mouth, urine retention, and constipation when compared with fluoxetine (Reference 2).

Clomipramine is typically used for canine separation anxiety and urine marking in cats. However, it has seen use to calm “bully” cats that pick on their more timid housemates (reference 4), due to its antihistamine effect.

BUSPIRONE

Buspirone is another drug used in cat behavior. This drug binds directly to serotonin receptors to reduce anxiety and promote boldness (Reference 2).

Buspirone reaches full effect in 1-2 weeks. Cats on Buspirone are more friendly and socially assertive. Because the drug promotes boldness, it can make aggressive cats more aggressive. It is primarily used to treat fearful, non-aggressive cats for urine marking and in cases of inter-cat aggression (Reference 2).  Victim cats on buspirone are bolder and are less likely to behave like “prey” when around more aggressive cats.

How Do I know if the drug is working?


To determine if the drug is working, you must “measure” the behavior regularly and compare it to the behavior you observed before starting the medication (Reference 1).

Before Starting the medication

  • Identify the problem behavior.
  • What are the characteristics of the problem?
  • How often does this occur?
  • Where does it occur?
  • Can you assign an intensity to the behavior? 10 for very intense, 0 for calm, relaxation?
  • How long does an episode last – how long before the cat becomes calm again?

It can be helpful to draw a house map and note on it where the behavior occurs.

House Map
A house map showing areas where house-soiling has occurred.

Once the medication starts…

Maintain a daily diary of the behavior. Look for trends showing that the behavior is not as frequent, not as intense or prolonged (Reference 1).

Keeping a Diary


Back to our cat who had her world turned upside down with a new dog or baby. She is hiding and not always using her litter box.

 

HIDING

The owner can record how often and/or how long the cat hides under the bed.

HOUSE-SOILING

In this case, monitoring involves checking the house for soiled areas and noting if the cat has soiled these areas.

The number of house-soiling/hiding incidents should decline if the drug is working once there has been enough time for it to reach full effectiveness.

Serotonin Syndrome


Too much serotonin can be fatal. Watch out for:

  • accidental overdose
  • combining two or more medications that act on serotonin
  • combining supplements that boost serotonin levels with medications such as fluoxetine, clomipramine and buspirone.

Signs of serotonin Syndrome

  • agitation, restlessness, aggression
  • tremors, ataxia, seizures, coma
  • vomiting, diarrhea, lack of appetite

Seek emergency treatment immediately if your cat takes a behavior drug and you see these signs!

A daily behavior medication for a cat can help reduce anxiety and aggression to a level where the owner can start a behavioral modification program. Even in cases where the owner is already following a behavioral modification program, medication can help improve the effectiveness of the program. These drugs, under a veterinarian’s supervision, are safe and can improve feline welfare. Maintaining a daily diary of behavior incidents is an important part of assessing the drug’s efficacy.

references

  1. Denenberg S, Dubé MB. Tools for managing feline problem behaviours: Psychoactive medications. Journal of Feline Medicine and Surgery. 2018;20(11):1034-1045. doi:10.1177/1098612X18806760
  2. Herron, M. Integrated Care: Feline Psychopharmacology, Nutrition, & Supplements. Presented at: 2022 American Association of Feline Practitioners Conference, Pittsburgh, Pennsylvania. October 27-30, 2022
  3. Bamalan OA, Moore MJ, Al Khalili Y. Physiology, Serotonin. [Updated 2023 Jul 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545168/
  4. Capuzzi, Joan. Medicine to Ease the Feline Mind. dvm360.February 2023 Vol. 54 , Issue 2, p. 16 January 4, 2023. https://www.dvm360.com/view/medicine-to-ease-the-feline-mind. Viewed 5/2024.