How to help your cat lose weight

Posted on March 6, 2022March 6, 2022 by felinepurrspective_u3q4o6

Your cat went in for her annual exam and your vet suggests that she lose some weight. Most likely, you were also given some daily calorie estimates and food amounts. Perhaps your vet recommended a weight loss food. What’s next?

Three ways to help your cat lose weight:

portion control
feeding multiple small meals
keeping your cat moving

Portion Control

If you have not done this already, measure how much your cat is eating. Make sure to include treats and table scraps. If your cat is a grazer, put out a measured amount of food in the morning and measure what remains the next morning, 24 hours later.

Gradual weight loss is best. The rule of thumb is to cut your cat’s food portion by no more than 10-20% at a time. Drastic food reduction can lead to a cat who is frantic for food, begging and sometimes biting you in his quest for food. It may take some time to reach the calorie allowance recommended by your vet.

The Behavior of Feeding: Multiple small meals daily

Now that you know how much to feed, let’s look at how you feed. Cats have small stomachs; in the wild, they follow a nocturnal schedule, hunting and feeding about 4 times, starting in the late afternoon and finishing in the morning. In between hunts, the cats nap and groom; sometimes they play with the kittens.

Your cat is designed to eat multiple small meals a day. If your cat is a grazer, this is what she is doing and she may be fine with her portion set out in a bowl for the day. Other cats may want to eat everything at once, which can lead to GI upset and boredom. To help your cat lose weight, portion control can be done by using a timed feeder or you can follow a feeding schedule. Here is a sample schedule for a working owner feeding 4 meals a day.

AM before leaving for work – meal feed: canned or dry food
Day Time: food puzzles or feeders with dry or canned food
PM arrive home from work – meal feed: canned or dry food
Bedtime Snack: Treat Time – treat toss or training

Strategies for the Multi-Cat Household

Life is rarely simple – often you have one cat who needs to lose weight and a “skinny” one who is a “grazer”.

Technology to the Rescue: Microchip feeders

SureFeed Microchip Pet Feeder:

Surefeeder for Cat — Athena’s Surefeeder opens only for her. Note the bubble on the back to keep the other cats out.

This plain vanilla feeder is ideal for grazers who tend limit themselves. The feeder is programmed to sense an individual cat’s microchip and only opens for the particular cat. Put the “skinny” cat’s food in the Surefeeder and the “fat” cat’s food in a timed feeder or in bowls spread out through the house. The Surefeeder can also accommodate canned food.

Timed Microchip Feeders:

These feeders sense the tag on the pet’s collar and allow a pet a certain amount of time to eat. Many of these feeders can accommodate more than one pet if they are eating the same food. However, some reviews note that a persistent pet will refuse to leave when the doors try to shut, keeping his head in the bowl and continuing to eat.

The Meowspace:

This is a ventilated transparent “box” with an access door. Some models have a microchip flap while others have a magnetic flap. The Meowspace also has a timed access option, allowing the cat to access the “space” only at certain times of the day.

The DIY version: You can make a “meow space” out of a closet by installing a microchip cat flap in the closet door. To add a “timed” option, place an inexpensive automatic feeder in the closet.

Low Tech Solutions to help your cat lose weight:

Some cats prefer to be up high while others are “ground dwellers”. If this is the case, you can feed the cats who climb up high on a shelf, top of a bookcase, or on the upper level of a cat tree while the other cat eats at ground level. Another option is to meal feed and separate the cats in different rooms when feeding.

keeping your cat moving

In the wild, cats prowl around looking for food. You can mimic this behavior by placing portions of food in different places around the house. Your cat has to go look for it. This is the idea behind Doc & Phoebe’s indoor hunting system.

Puzzle feeders also can also stimulate and engage your cat while feeding. Make sure to introduce your cat to his puzzle feeder gradually, increasing the food in the puzzle and decreasing his food in the bowl as he learns to use the puzzle feeder.

Using the indoor hunting system or puzzle feeders can be challenging in the multi-cat home: some cats will catch on more quickly than others, getting more to eat in the process. Indoor hunting and food puzzles may not be appropriate. In that case, help your cat lose weight by engaging him in a daily play session or taking him for a leash walk outside.

Treat Toss
If you are feeding dry food, you can make one of the meals a tossing game. Dental treats or dental kibbles are large and can be tossed for your cats to hunt down. Space the cats out so each cat has his own “territory” to hunt in and make the rounds, tossing the kibbles. This is also a great way for the cats to interact with guests, who usually enjoy tossing the treats to the eager felines!

Help your cat lose weight – reduce his risk of medical problems such as diabetes and arthritis, and form a closer relationship with your cat through daily play and exercise activities.

Want to keep up with the world of cats? Subscribe to The Feline Purrspective!

Arthritis in cats: a tale of biotech and a Chinese hamster

Posted on January 30, 2022 by felinepurrspective_u3q4o6

If you search for “monoclonal antibodies”, most of the search results are about COVID-19 and its variants. But did you know that monoclonal antibodies form the basis of the newest treatment for arthritis in cats? This new treatment is called Solensia. Solensia is a monthly injection for arthritic cats that won FDA approval this month. It should be available through your veterinarian later this year.

arthritis in cats: a tale of biotech and a chinese hamster

what are monoclonal antibodies?

Monoclonal: refers to a cell or organism that comes from a single individual or cell.
Antibodies are proteins in the blood that our immune system produces to counteract a foreign substance such as a bacteria or virus (think COVID-19).

antibodies and the immune system

Immune cells in our bodies called B-lymphocytes mount a response to a foreign substance or antigen (e.g. a virus), binding to it and deactivating it. The presence of the antigen and immune cells called T cells activate the B-cells. The B cells then propagate and release antibodies that are able to bind to and deactivate the specific antigen that stimulated their formation!

Monoclonal antibodies are derived from clones or copies of activated B cells. They can be harvested and grown in the laboratory and used to fight infections caused by the antigen they were developed to target.

Where do monoclonal antibodies come from?

Blood cells from convalescing patients: Due to the large numbers of convalescing COVID patients, there was a ready source of blood cells containing B-cells with antibodies to COVD 19 that could be used to make monoclonal antibodies to treat newly infected patients.
Transgenic mice: Mice that have been genetically altered to carry human antibody genes instead of mouse antibody genes are the usual source for monoclonal antibodies. These mice can be injected with a specific antigen and produce fully human antibodies that can be used by human patients to combat that antigen. Being human antibodies, they are less likely to be rejected by the human immune system.

Arthritis in cats: using monoclonal antibodies

Nerve growth factor (NGF) is a protein that is key to the development and survival of nerve cells or neurons, particularly sensory neurons that transmit pain, temperature, and touch sensations.

When NGF binds to pain receptors inside the sensory neuron, a series of events is triggered that ultimately sends a “pain” signal to the brain.

Instead of binding to a structure on a virus, monoclonal antibodies can be developed to recognize and attach to NGF, preventing NGF from binding to the pain receptors on the sensory neruron, blocking the pain signal.

Motion is Medicine

A reduction in pain means our arthritic cats will be more likely to move around more. Increased mobility will strengthen the cat’s muscles, so they can better support and assist the deteriorating joints. Increased activity and reduced pain result in a better quality of life.

Biotech Magic

The active ingredient in Solensia is frunevetmab, a monoclonal antibody that targets NGF. The antibodies are sourced from Chinese hamster ovary cells. Like the mice that have human antibodies instead of mouse antibodies, the hamster cells are “felinised”using recombinant biotechnology. Sections of the hamster antibodies are replaced with their feline counterparts. “Felinization” ensures that the cat’s immune system will not reject the monoclonal antibodies but allow them to function as part of the cat’s immune system.

Of cats and hamsters: no hamsters harmed

Frunevetmab is sourced from the cells of Chinese hamster ovaries. In fact, cells from an individual Chinese hamster, harvested back in the 1950s, produced the cell line which dominates biotechnology today. These cells are easy to propagate and maintain in the lab, providing a ready source of monoclonal antibodies.

multimodal therapy for arthritis in cats

Solensia is a pain medication and does not directly aid in preserving the synovial tissues. Most likely, Solensia will be part of a multimodal treatment that will include drugs and supplements like Adequan or glucosamine that are thought to help maintain synovial tissues in addition to weight loss and exercise.

Unlike other arthritis pain treatments such as NSAID’s, monoclonal antibodies are eliminated in the same way other proteins are, with minimal effect on the kidneys and liver, a concern for our cats with Chronic Kidney Disease.

Treatment using Solensia will consist of monthly injections under the skin. Most cat owners can become proficient in giving subcutaneous injections and treatment can be done in the safety and comfort of the cat’s home.

Thanks to a Chinese hamster years ago and advances in biotechnology, our cats may be able to spend their “ golden years” without pain from osteoarthritis!

Want to keep up with the world of cats? Subscribe to The Feline Purrspective!

Medication before your cat’s vet visit

Posted on January 23, 2022January 25, 2022 by felinepurrspective_u3q4o6

Many of us (cat owners) dread taking our cat to the vet. There is the ordeal of the carrier and car trip; once there, your cat seems miserable. However, regular veterinary care is the key to a happy and longer life for your cat. Can medication before your cat’s vet visit help?

Not every cat needs medication at the vet. Some cats are fine just having some familiar things with them. Familiarity can help reduce situational anxiety – the anxiety you experience when you are in a strange place. Things we can do to increase familiarity for your cat at the vet visit include:

Training her to be comfortable in her carrier
Choosing a carrier with a removable top to allow examination in her carrier
Getting her used to the car and taking her on some drives that don’t end up at the vet
Bringing your cat’s favorite treats
Spraying the carrier with pheromones (Feliway) before the visit

For some cats, this may not be enough. Your usually nice kitty becomes a raging demon or just freezes like a rock and doesn’t move – both reactions can be the result of anxiety and fear.

I recently took my youngest cat in a for a rabies vaccine and to have a tooth evaluated. Gus accepted handling and food but had a whopping heart rate of 230 beats per minute! He was anxious even though I was there with him.

We would like our cats to associate good things with going to the vet but they may not be feeling well when they are there or they anticipate getting poked with a needle for vaccinations or blood tests. So, when the carrier comes out, your cat may associate it with negative emotions and understandably becomes anxious.

Anxiety actually has a function in our lives – worrying about something in the bushes pouncing on you probably saved a lot of cavemen and feral cats; anxiety can improve your physical and mental performance. But anxiety at the vet clinic does not benefit your cat and can actually make things worse. An unpleasant visit can become an unpleasant memory.

Medication before your cat’s vet visit

Have you ever had elevated blood pressure at a doctor visit? Anxiety before medical appointments is common for people as well as cats. Because cats don’t speak human language, we can’t reassure them and let them know exactly what is happening. It is worth considering medication before your cat’s vet visit to help reduce his anxiety.

Gabapentin and trazodone are two medications commonly used to reduce the stress of the vet visit. These medications must be prescribed by your veterinarian.

Gabapentin

Developed as an anti-convulsant
Has anti-anxiety properties – reduces the release of excitatory neurotransmitters
Is a pain reliever

Gabapentin is commonly used in the veterinary practice to reduce anxiety in cats. There have been a few studies evaluating fear and stress in cats having taken gabapentin – these studies found a reduced CSS (cat stress score) after administration of gabapentin.

The typical dose is 100 mg given 1.5 – 2 hours prior to the vet visit. Frequently, a dose is also given the night before. Doses can vary for individual cats – some cats may do well with a 50 mg dose while others may need 150 mg.

Gabapentin is available in capsules, liquid and small tablets.

Capsules: The capsule is opened and the powder is mixed in a small amount of tuna fish or canned cat food. Gabapentin is bitter and some cats may not eat it in food. The capsules may also be given using a pet piller or a squeeze up treat.
Liquid: The liquid may result in foaming at the mouth.
Tablets: Gabapentin can also be compounded into small, flavored tablets – these can be given in pill treats.

Your cat may be a little sleepy or wobbly after taking gabapentin. You may want to watch kitty near the stairs or jumping up on things!

Gabapentin is a pain reliever for cats – reducing pain may be one of the ways it helps reduce anxiety and fear

Trazodone

Antidepressant that is commonly prescribed for insomnia and depression in humans
One of its side effects is drowsiness

There have been a few studies looking at cats receiving trazodone. One study in particular found that the CSS (cat stress score) was the same in the treated group as the group receiving the placebo. So, trazodone appears to be more of a sedative (makes you sleepy) than an anti-anxiety drug.

Typical dose is 50 mg given by mouth 90 minutes before the stressful event.

Can result in lower blood pressure in cats
There is a risk of serotonin syndrome if used with other anti-depressant medication such as fluoxetine (Reconcile).
Available as a tablet or can be compounded into a liquid or capsule form.

There is increased interest in identifying medications to reduce stress and anxiety in cats at veterinary visits. We should expect to see more medications becoming available in the near future.

Medication before your cat’s vet visit can be part of a low-stress veterinary visit. However, it will be most effective when combined with training to reduce situational anxiety and low-stress handling techniques.

As for Gus, I will make sure to give him some gabapentin before vet visits.

Want to keep up with the world of cats? Subscribe to The Feline Purrpspective!

Arthritis Supplements for cats – do they work?

Posted on December 19, 2021 by felinepurrspective_u3q4o6

A cat receives an injection of polysulfonated glycosaminoglycans.

It is thought that almost 40% of all cats have clinical signs of arthritis and 90% of cats over age 12 have damage to the joints that you can see on x-rays. Cats are such masters at hiding pain that we are now thinking that arthritis is there earlier, pain is happening and we may not be able to see it on x-rays yet.

What if we could be proactive and start some kind of treatment before our cats even seem painful? Could we slow the deterioration of the joints? What arthritis supplements for cats are available and do they work?

The motivation behind writing this post was to help my youngest cat, 5 year old Gus, who showed some indications of spinal arthritis in his x-rays. Should I begin a supplement with him? I was astounded by the sheer numbers of arthritis supplements for cats on the market and the astounding claims they made.

arthritis supplements for cats – do they work?

Arthritis supplements for cats on the market now range from supplements used by humans to homeopathic remedies. Clinical trials are rare to non-existent on many of these products. This post addresses the more common products and ones that have had some double-blinded clinical studies done.

glucosamine/chondroitin,
omega fatty acids/ green lipped mussel extract
polysulfated glycosaminoglycans

Glucosamine/chondroitin

Glucosamine occurs naturally in cartilage, the flexible connective tissue found throughout the body – for example, in the external ears and the surfaces of joints. The supplement can be made synthetically in the lab or harvested from the shells of shellfish.

Some human studies have shown oral glucosamine may help with pain relief and slowing of joint degeneration in people suffering from osteoarthritis. However, in general, the results from these studies are not conclusive.

Dasuquin is a commercially available formulation of glucosamine/chondroitin for cats. It is a dietary supplement in a capsule that is sprinkled on food. The product has been evaluated for safety.

A recent double-blinded study of Dasuquin enrolled 59 cats with Degenerative Joint Disease.

All 59 cats were given a placebo for 2 weeks.
Then 29 cats received the supplement for 6 weeks while another 30 continued to receive the placebo.
The cats were evaluated by using an at-home accelerometer (like a kitty “fit bit”), owner observations and vet exams through out the study.
The study showed a strong placebo effect – 78% of the cats were more active while on the placebo.
Cats on the supplement did not show any statistically significant improvement over cats on the placebo.

However, the study did raise some questions:

The “kitty fit-bits” showed that the least active cats at the start of the study became more active on the supplement. Were these cat more painful to begin with?
The placebo was given in the first two weeks of the study when owner enthusiasm would have understandably been highest and owners would have been looking for improvement.

More research is needed – perhaps a different study design?

Omega Fatty acids (fish oils)

Supplementation with fish oils has shown some benefit for arthritic cats. A double-blinded study showed that cats supplemented with fish oil for 10 weeks were more active, going up and down the stairs more, jumping higher, not walking as stiffly and were more interactive with their people. This study used owner evaluation to assess the cats’ improvement.

Fish oil can be given as a dietary supplement (Welactin) or fed as a therapeutic diet, such as Hill’s j/d.

Side effects of fatty acid supplementation include GI upset and reduced blood clotting. There is some controversy over how much fish oil is enough. Additionally, fish oil can add quite a bit of calories to your cat’s diet and could result in weight gain, taxing your cat’s joints further.

Merial’s Antinol for Cats supplement is based on fatty acids from green-lipped mussel extract. There are a number of case studies where the supplement has been given to cats with good results for cardiac and dermatological issues, in addition to joint and mobility problems.

Polysulfated Glycosaminoglycans (PSGAGs)

This product is available under the brand name Adequan. It is the veterinary version of Arteparon, used in humans.

Decreases the breakdown in cartilage. The PSGAG’s allows the cartilage to hold more water, making it resistant to degradation.
Adequan has been extensively studied in dogs and horses for over 20 years and is FDA-approved for these species
Available by prescription.
Given by subcutaneous injection in cats with generally good results.

The jury is still out on most of the arthritis supplements for cats. Given at the manufacturer’s recommended dose, these products are safe and may be effective. Considering the individual nature of pain, some cats may respond favorably while others do not. Once again supplements are basically unapproved drugs so there is not the rigorous evaluation that accompanies FDA approval.

Your vet is your best resource on arthritis supplements for cats. He or she will be able to recommend a supplement or diet that is appropriate for your cat and is compatible with other medications or medical conditions your cat may have. In particular, combining supplements should be done with care – glucosamine, fatty acids and Adequan all effect how your cat’s blood clots.

So, what will I do for Gus?

My vets recommended the Adequan injection, citing the robustness of the canine studies and the fact that it is an injection – there is a greater confidence that the cat will get the supplement. We are not depending on him to eat something.

Want to keep up with the world of cats? Subscribe to The Feline Purrspective!

Measuring your cat’s blood pressure: why and how

Posted on December 12, 2021 by felinepurrspective_u3q4o6

HDO BP cat — A cat relaxes in his basket during a blood pressure reading at home using an HDO unit. The cuff is on his tail. The blood pressure wave is on the computer screen.

You’ve brought your senior cat in for her regular checkup and the technician asks you if you would like to have her blood pressure checked. Although your blood pressure is routinely checked when you go to the doctor, it has not occurred to you to ask to have your cat’s blood pressure checked. Should you have your cat’s blood pressure measured? How is it done – will it be uncomfortable? Frightening?

Why measure your cat’s blood pressure

As cats age, many develop hyperthyroidism and kidney disease. Other cats may develop diabetes. All of these conditions can result in the heart pumping harder to compensate for the changes. As the heart pumps harder, blood pressure increases and arteries, the eyes, the kidneys, the brain and heart can be damaged.

Left untreated, high blood pressure can result in:

blindness
increasing loss of protein through the kidneys >> shortened life span
disorientation, lack of balance, seizures, altered mentation or behavior, or weakness in the limbs

The best way to avoid these consequences is to monitor your cat’s blood pressure and start treatment if his blood pressure is high.

So how do we measure your cat’s blood pressure?

When measuring blood pressure in humans, we typically place a pressure cuff on the upper arm, inflate the cuff until the flow of blood to the artery is shut off . The cuff is then released, and a wave of blood fills the artery, turbulent at first, then subsiding to a smooth flow.

The human practitioner can use a stethoscope to listen to the sounds made as the blood rushes back into the artery.

The first sound is heard at the systolic blood pressure (the higher number in 120/80)
The final sound is heard at the diastolic pressure (the lower number in 120/80).

We will also use a blood pressure cuff to measure your cat’s blood pressure. This cuff can be put:

on the front leg
on the hind limb, above or below the hock (ankle)
on the tail

Cats’ arteries are much smaller than humans’ and it is difficult to hear the sounds of the blood flow using a stethoscope, so we turn to other methods: Doppler and oscillometric.

Doppler

A Doppler unit measures blood flow.

After placing the cuff on your cat, the Doppler sensor is placed over the target artery.
Piezoelectric crystals in the sensor detect changes in the flow of blood in the arteries and convert these to sound.
Acoustic gel on the sensor ensures good contact so that the practitioner can hear the heartbeat.
The cuff is inflated until the heartbeat is no longer heard.
The cuff is then released and the pressure at which the heartbeat can be heard again is the systolic blood pressure.
Headphones are usually used when measuring blood pressure with a Doppler.

Doppler units give us a measurement of the systolic blood pressure, the larger number in the 120/80.

Oscillometric

Only a cuff needs to be placed to measure your cat’s blood pressure with an oscillometric unit.

A sensor in the cuff detects the pressure pulses in the artery.
As the cuff is inflated, the pulses decrease as flow to the artery is cut off.
The cuff is then deflated and the pressure wave that results as the blood rushes back into the artery is analyzed.

Oscillometric units typically only measure the peak of this wave, the average blood pressure, and calculate the systolic and diastolic pressures.

A High Definition Oscillometric unit records the entire pressure wave, directly measuring the systolic and diastolic pressures. An HDO unit is usually connected to a computer to view the pressure wave and determine if the measurement was accurate.

How accurate is a blood pressure if my cat is nervous at the vet clinic?

Just like people, cats get anxious and nervous when visiting the vet clinic. Blood pressure is sensitive to this and it can be a challenge to measure your cat’s blood pressure.

Putting the odds in our favor:

Most of the time, you should be with your cat during a blood pressure measurement. Your cat knows you and trusts you. Your presence is reassuring and calming.
Allow your cat to settle in for 5-10 minutes – the measurement should be done in a quiet room.
If your cat likes to snuggle in your lap, see if the measurement can be done there. If your cat prefers to sit on his stomach, perhaps a tail measurement is best. If he is comfortable laying on his side, a hind leg may be better.
Using the front leg to measure blood pressure puts the practitioner in front of the cat; curious cats may want to take a nibble at the blood pressure cuff. I prefer that your cat be facing you, her person, who can reassure her. I feel the tail and hind leg work better.
The artery being measured, tail or hind leg, should be at the same level as the heart – so kitty should not be sitting up, but laying comfortably on his stomach or side.

What do the numbers mean?

Again, like people, the systolic pressure is ideally around 120.
Pressures 150 and over can indicate the need for medication.
Your vet may also do an eye exam, looking at the eye with an ophthalmoscope or lens. In some instances of high blood pressure, the vessels in the eye dilate and become twisted; sometimes the retina may be detached, resulting in blindness. If high blood pressure is caught early enough, blindness may resolve with treatment.

My cat’s blood pressure is high but her eyes looked OK. What next?

High blood pressure can be treated with drugs – the most common drug used is oral amlodipine. Amlodipine takes effect fairly quickly and a blood pressure can be repeated in about 10 days and the dose adjusted if needed.
Other medications such as benazepril or telmisartan may be used alongside or in place of amlodipine.

I don’t think the reading was accurate – my cat was too nervous

It is worth investing in a home blood pressure visit. A practitioner can come to your home and get a measurement where your cat feels safe and secure.

Measuring your cat’s blood pressure especially as she gets older will help keep her healthy and comfortable. Without treatment, high blood pressure can have serious side effects, including blindness, seizures, and cardiac damage.

Have your cat examined regularly by your veterinarian, as changes to the eyes or a heart murmur might warrant a blood pressure check.

Want to keep up with the world of cats? Subscribe to The Feline Purrspective!

Cat dementia – Three cats and three outcomes

Posted on November 14, 2021 by felinepurrspective_u3q4o6

Identifying signs of cat dementia is not always straightforward. In the hubbub of daily life, behavior changes can be subtle and go unnoticed until they are more severe.

Changes in behavior can indicate if your cat’s mental state has changed. The acronym VISHDAAL summarizes the behavior changes we need to observe to care for our senior cats.

V = changes or increase in vocalization
I = changes in interaction with us and other pets
S = changes in sleep-wake cycle: restlessness, night time activity
H = housesoiling
D = disorientation and confusion
A = changes in activity
A = anxiety
L = learning and memory

Three cats – three outcomes

rupert, 18 year old neutered male siamese

I had two senior Siamese cats when I had my first child. A first-time mom, I was frazzled, dealing with the completely new experience of parenting and was not paying as much attention as I should have to my cats.

One day, an acquaintance asked why one of the cats, Rupert, was sitting on the kitchen counter, in a corner, facing the wall. I had been aware that he did that sometimes but when I paid closer attention, I found that he would eat in the morning, use his litter box and then spend the day on the counter, facing the wall. He would come down to eat, drink, and use the litter box but always returned to the counter.

Behavior Changes – signs of cat dementia?

I – Rupert was no longer interacting with us.
D – He seemed confused and “out of it” – sitting on the counter all day
A – His activity had changed – he did not move much from the counter

Diagnosis:

Rupert had lost quite a bit of weight, although he was eating well. My vet diagnosed him with hyperthyroidism, which was a new disease in cats at that time.

Outcome:

Use of radioactive iodine to treat the disease was pioneered about 10 years earlier but it was not commonplace. Surgery was an option but at 18 years of age, Rupert was not a good candidate for surgery and we elected euthanasia due to his declining Quality of Life.

The Takeway:

I suspect that Rupert had moderate to severe cat dementia. The symptoms were most likely apparent earlier and I just did not recognize them. Nowadays, drug therapy for hyperthyroidism is readily available – methimazole is an FDA approved treatment for hyperthyroid cats. Perhaps treatment of the hyperthyroidism would have reduced the symptoms of cat dementia enough for Rupert to have had some more time with us.

Athena, 16 year old spayed female

Athena had been slowing down over the past year, was not eating as well and was spending most of her time sleeping. We had provided her with steps to access window perches and our bed; we also provided her with a heated bed.

Behavior Changes – signs of cat dementia?

I – Although still willing to play, Athena was interacting less with us; she had previously been a “nosy, busybody” kind of cat.
A – Athena no longer went on her daily walk and was less active in general

Diagnosis:

Diagnostic blood work did not show any significant changes over the past year. Athena did not show other signs of cat dementia and would still learn new tricks when hungry for treats.

X-rays showed moderate to severe arthritis in one of her hips and knees. We decided to treat her arthritis pain with the drug gabapentin.

Outcome:

Treatment for her arthritis pain has been a game changer for her; her activity level has increased, her appetite has increased, and she is back to “being in your face” when she wants something.

The Takeaway:

Regular checkups and treatment of chronic conditions can make you and your cat happier! Some symptoms typical of dementia may be due to treatable, medical conditions.

Marley, 15 year old neutered male

cat with food puzzle — Marley works the Poker Box, a food puzzle.

Marley is a friendly, affectionate cat with good health overall. In the past several months, Marley showed some of the behavior changes that we need to monitor in senior cats.

Behavior Changes – signs of cat dementia?

I – Marley had become more clingy than usual and more interactive
D – He seemed confused when playing the nightly game of “treat toss” – he seemed to forget that he was chasing a treat!
A – He did not want to walk outside with us (which he has been doing for years).
A – He seemed anxious and a little fearful. His interactions with the other cats became timid.

Diagnosis

Marley’s senior exam and blood work did not reveal any abnormalities other than a slight decline in kidney function which could be expected at his age.

Marley appears to have some mild cat dementia. Since these changes were mild, we decided to try SAMe, a dietary supplement. SAMe has been shown to be effective at reducing symptoms of dementia in cats in the early stages of cat dementia.

Outcome

About 2 months have gone by with daily supplementation. Marley is taking his daily walk again and is not as clingy with his humans. He is no longer stand-offish with the other cats and is “catching” his treats again when we play the nightly treat toss.

A Final Word…

Cat dementia cannot be cured but it can be managed. With early diagnosis, appropriate environmental modifications, dietary supplements, therapeutic diets, and medication can help can reduce the symptoms of dementia and improve Quality of Life for both you and your cat.

Want to keep up with the world of cats? Subscribe to The Feline Purrspective!

Cats and Pumpkin

Posted on October 31, 2021 by felinepurrspective_u3q4o6

It’s that spooky time of year where black cats and pumpkins are all the rage. But did you know that many cats dine on pumpkin year round? Why add pumpkin to your cat’s diet? Does it work?

pumpkin and cats

Pumpkin is a popular way to add fiber to a cat’s diet. Fiber can be used to manage diarrhea, constipation, diabetes, satiety, and hairballs.
Fresh pumpkin is said to have about 3 g of dietary fiber per cup while canned pumpkin can have up to 7 grams per cup.

What is fiber?

The story about fiber is complex so I will just say that fiber is substances in food that cannot be digested by the enzymes in the small intestines. Fiber arrives in the large intestine undigested and unchanged.

Fiber can be soluble in water or not (insoluble).

Soluble fibers

Some soluble fibers form a gel in the intestines that slows digestion of carbohydrates, keeping blood sugar levels steady.
This gel may also block fat that would otherwise be digested.
Other soluble fibers ferment in the large intestine, forming the short chain fatty acids (SCFA) that are part of the cross-talk between the intestinal microbiome and the brain.

Insoluble fibers can pass through the GI tract intact and function to “bulk up” stool and help waste move through the gut.

THE TAKEWAY: It important to have the right amount of the right type of fiber.

Too much fermentable fiber can result in excess gas and gastrointestinal discomfort.
not enough insoluble fiber may result in diarrhea.

Fiber and carnivores

We tend to think of plants when talking about fiber. But our cats are obligate carnivores, meaning they mainly eat meat. Do they need fiber?

“animal fiber”

A wild cat will eat the entire mouse – fur, bone, cartilage, gut content, tendons, ligaments. These indigestible parts act as fiber – bulking up stool and helping waste pass through the intestines. Even the chitin in the wings of that grasshopper can function as fiber. Some of these materials ferment in the large intestine forming SCFA that allow the microbiome in the gut to talk to the brain.

A study looking at “animal fiber” compared a diet of whole rabbits (fur and all) versus supplemented beef for captive cheetahs. The cheetahs eating the whole rabbits had more SCFA in their stool than those cheetahs eating supplemented beef. The stools of the rabbit-fed cheetahs were also bulkier due to the “animal fiber”.

We don’t feed our cats whole rabbits – plant fiber is more easily sourced so commercial cat food includes these. Research has shown that feeding our cats moderate amounts of fermentable fiber such as beet pulp helps feed the intestinal microbiome without a lot of gas and bulky stool.

“Differences in fiber type and amount likely result in many of the gastrointestinal issues that pet owners see that vary with diet – they can often explain a pet who has poor stool quality on one diet but perfect stool on another. Too much or too little or the wrong mixture of fiber is a much more likely reason for a pet to not do well on a specific diet than a food allergy…” (from Fiber Frustrations, Cummings Veterinary Medical Center at Tufts University)

Back to Pumpkin and cats…

Pumpkin has both soluble and insoluble fiber. One tablespoon of canned pumpkin contains about 0.1 g of soluble fiber and 0.4 g of insoluble fiber. By comparison, 1 teaspoon of metamucil ( psyllium) provides 10 times as much fiber: 2 grams of soluble fiber and 3 grams of soluble fiber.

While pumpkin is safe for most cats, you may have to give a lot of pumpkin to match the level of fiber in say, one of the veterinary therapeutic diets. There are no real guidelines to supplementing fiber in commercial cat diets so talk to your vet if you feel that your cat needs fiber to manage diarrhea, constipation, or hairballs. Your vet can recommend a diet or supplement with the appropriate type and amount of fiber.

If you decide to supplement your cat’s diet with pumpkin, be sure to choose canned pumpkin and not pumpkin pie mix. While pumpkin and cats are a safe combination, the sugar and spices in pumpkin pie mix are not good for your kitty.

The nutritionists at Cummings Veterinary Medical Center (Tufts University) recommend that …“If supplemented, fiber should always be given gradually over a few days to weeks until the stool reaches the desired composition or other desired benefit is reached (or it becomes clear that it is not helping).”

Happy Halloween!

Want to keep up with the world of cats? Subscribe to The Feline Purrspective!

SUBSCRIBE!

Is my cat sick from stress?

Posted on April 23, 2021April 26, 2021 by felinepurrspective_u3q4o6

For a time, I lived in the Florida Keys, about 50 miles north of Key West. Half of the island where we lived was owned by the Nature Conservancy and was a natural habitat of mangrove swamps, alligators, snakes and raccoons. There were some feral cats in the Conservancy reserve.

One summer, there was a litter of 4-5 kittens that we saw playing with their mother near the side of the road. In a few weeks, these cats had disappeared with the exception of one little female kitten, who continued to return to the side of the road. We used a Havaheart trap to bring the small kitten home. It was October so we named the orange and black kitten Pumpkin.

Throughout her life, Pumpkin was prone to bouts of bloody urine and not using the litter box. Antibiotic treatment was palliative at best; x-rays and ultrasounds did not reveal any medical causes. She was affectionate but she did not like the other cats. She seemed happiest when my son took her with him when he moved.

Cats’ health and stress…

Veterinary medicine for cats has advanced in the past few decades. If Pumpkin were alive today, she might be diagnosed with FIC, or Feline Idiopathic Cystitis. Idiopathic means that although we recognize the condition we don’t know the cause of it; cystitis refers to inflammation of the bladder.

Cats that suffer from frequent FIC episodes handle stress differently than other cats – they do not release stress hormones such as cortisol in the same way “normal” cats do.

Cats prone to FIC

have lower levels of cortisol in their bloodstreams compared to “normal” cats.
have higher levels of the “fight-or-flight” hormones.

Like interstitial cystitis in humans, stress contributes to flare-ups of FIC, making a cat sick from stress.

Cortisol is a potent anti-inflammatory hormone – the lack of cortisol can result in increased inflammation in the body, in this case, the bladder.

Ways to Reduce your cat’s stress at home…

Cat napping on dresser — Gus takes a break on a blanket on a dresser.

Make sure each cat has a safe place – a place that is secure and secluded, a hiding place to retreat to.

Safe Place

Feeding stations for cats — Gus is much more relaxed when eating away from the other cats.

Have several feeding stations, water stations, and litter boxes spread through out the house or apartment.

House map cat resources — A simple sketch of your house can help with locating litter boxes.

Draw the paths a cat must take to get to her food, water and litter boxes in your house. Is there plenty of room for cats to pass other pets and humans?

cat with wand toy — Zelda plays with a toy mouse on a wand toy.

Good kharma with humans.

Greet your cat before handling him or her.
Have a daily routine for grooming and play.

Positive cat-human interactions

Marley marks the corner wall at the top of the stairs.

Cats communicate by smell.

Use pheromone diffusers in the safe places.
Don’t use of strong smelling cleaners.
Scoop litter boxes daily.

The Colony Scent

Outside the home – what can make a cat sick from stress

Your cat may view neighborhood cats or other animals coming to the windows and into the yard as threats to his territory. Territorial threats can make your cat sick from stress. Consider…

A cat fence can keep other cats from entering the yard
Have scratching posts at doors and windows so that the resident cats can mark their territory.
A motion-activated sprinkler can help deter animals from coming into your yard.

There is no substitute for appropriate and timely medical care. However, increased stress contributes to flare-ups of not only FIC, but other conditions such as chronic diarrhea and overgrooming.

Pumpkin lived to be 17 years old. She was euthanized due to complications of chronic kidney disease. I wish I knew then what I know now – her life may have been less stressful and more comfortable.

Plant Based Cat Food – Does it Have What Cats need?

Posted on March 14, 2021 by felinepurrspective_u3q4o6

I have been trying some plant-based milks. My most recent purchase was oat milk, fortified with other plant proteins, so that the protein content is similar to that of cow’s milk. While I was having cereal, I was mobbed by three of my cats who demanded a taste. All three liked the oat milk, and now recognize the jug, asking for more.

I am aware that oats can be in pet foods, so a taste of oat milk occasionally should not be a problem. Cats often like cow’s milk but are lactose intolerant. Oat milk does not have lactose.

Was the plant milk appealing because of the added protein? This brand claimed to have the 9 essential amino acids that human adults need and as much protein as cow’s milk.

What amino acids do cats need? Could plant based cat food be healthy with the right supplements?

Cats are what we call “obligate carnivores” -they evolved to eat meat, unlike dogs and humans who are omnivores (eat a combination of plant and animal foods). Cats not only need protein from meat for repairing and building tissue and regulating their metabolism – they need protein to provide energy.

There are 20 amino acids that make up proteins. Human bodies can make 11 of these 20 amino acids – the rest we have to get in food.

Amino acids that we must get from food are called essential amino acids.

Cats can synthesize 9 of the 20 amino acids. Their diet must provide the remaining 11: 9 essential amino acids that we humans require plus 2 additional ones: taurine, arginine.

What happens if a cat does not get Taurine and Arginine?

Not Enough Taurine…

blindness due to retinal degeneration
heart failure
reproductive issues
abnormalities in the central nervous system

Not enough Arginine…

high amounts of ammonia in the bloodstream
seizures and death

Cats need Taurine! — Taurine is a popular supplement in human energy drinks.

Sources of taurine and arginine in nature: animal tissues such as meat, fish and eggs!

What else do cats need to get in their food? Niacin, vitamin A, and vitamin D – their bodies do not make these vitamins.

What if we supplement plant based cat food with taurine, arginine, vitamins…

Proteins can be found in plants as well as animal tissues (meat). However, whereas animal tissues are “complete” and provide all the essential amino acids, plant sources are not “complete”. Taurine is not found in plants.

Now we arrive at the question of digestibility – sufficient amounts of the amino acids and vitamins must be digested from your cat’s food to be available to her body.

Plant based proteins are not as digestible as animal proteins. Plant protein has a different structure than animal protein and there are chemical compounds in plants that affect how well your cat’s digestive enzymes break down her food.

Recent research indicates that it is the “non-protein” part of whole grains that affects the digestibility of plant proteins. One finding in this 9 year study was that cats were able to digest appropriately processed plant proteins such as corn gluten as well as they digest chicken and fish proteins.

The Future of Cat Food

There is an ethical and economical drive to reduce the carbon footprint of companion animals and one way is to reduce their consumption of meats sourced from livestock bred for this purpose. Increasing the amount of plant protein in commercial cat food is the subject of current research.

There are some plant based cat foods already on the market. However, I was not able to find ones that advertised having done AAFCO feeding trials. There are concerns about nutritional adequacy with these foods. Personally, I am not ready to risk my “fur babies” on these foods yet.

I feel we will see more plant-based foods for our cats in the future. In the meantime, make sure your cat’s food has taurine, arginine, niacin, Vitamin A and Vitamin D in addition to plenty of “complete” protein.

Make sure to feed your cat a diet formulated for cats. Dog food typically does not contain the taurine, arginine, niacin, and vitamin A required by cats.

Using CBD for Your Cat to manage pain and anxiety

Posted on February 28, 2021February 28, 2021 by felinepurrspective_u3q4o6

Cat sniffs cannabis plant — Background by Next Green Wave on Unsplash

CBD for Your Cat?

CBD, short for cannabidiol, is an increasingly popular supplement. It comes from the hemp plant, a cousin to the marijuana plant. It does not get you “high” like marijuana.

CBD supplements are used to manage anxiety, insomnia and chronic pain. Recently, Epidiolex, a medication containing CBD, has received FDA approval to treat seizures resulting from several rare forms of epilepsy. Apart from Epidiolex, CBD is marketed as a supplement, not a medication. The FDA does not regulate the safety, purity or efficacy of supplements. You don’t know for sure if the product you buy actually has the active ingredients listed.

Can you use CBD for your cat to manage anxiety and pain?

The Endocannabinoid System (ECS ) is a complex cell-signaling system in the bodies of animals, both vetebrates and invertebrates. It was identified in the early 1990s by researchers exploring THC (tetrahydrocannabinol), a well-known cannabinoid found in marijuana. The ECS helps maintain a balance among the physiologic processes in the body.

Your body produces chemical compounds called cannabinoids that bind to cannabinoid receptors in the bone, brain, heart, liver, spleen (all part of the ECS) and regulate processes in your body. The ECS is thought to reduce inflammation, pain and stress.

CBD is a cannabinoid and can bind to the receptors in the ECS. While it is exciting to think that we may soon be able to supplement our own ECS (possibly our cat’s ECS) to manage anxiety and pain using CBD, the problem is that we don’t know much about CBD. There are few scientific studies regarding its effects and dosing in humans, much less cats.

Cats are not little people in fur suits…

Cats’ DNA lacks certain genes that code for some of the enzymes that metabolize human drugs and supplements. Notable examples are aspirin, acetaminophen and ibuprofen.
The length of time a drug stays in your cat is different than how long it remains in your body. Cats are smaller; their gastrointestinal tracts are different than ours.
Side effects in humans include drowsiness, mood swings, decreased appetite, and diarrhea – we don’t know if cats would experience the same side effects

CDB oil is typically administered to cats and dogs orally, in food or treats. These are supplements – you have to rely on the CBD manufacturers to regulate themselves. You don’t always know if the product actually contains CBD or how much CBD. There are few clinical studies to guide with dosing CBD for your cat.

The National Animal Supplement Counsel is a group of supplement manufacturers that is trying to regulate the safety of commercial supplements. They require their members to provide a certificate of analysis indicating potency, per-dosing unit, all ingredients and the presence of metals or pesticides.

If you would like to try CBD for your cat, do so under the supervision of veterinarian who has experience with prescribing CBD. He or she can recommend a particular brand, a dose for your cat, and monitor of kidney and liver values if needed while kitty is on CBD.

Above all…
PLEASE do not expect supplements or drugs to substitute for providing your kitty with an environment that he will thrive in. Make sure your cat’s habitat makes him feel safe and secure by meeting his behavioral and emotional needs.

a safe place
multiple, separate resources
regular and predictable human interaction
opportunity to hunt
a habitat that maintains the colony scent